Functional variations in MBL2 gene are associated with cutaneous leishmaniasis in the Amazonas state of Brazil
نویسندگان
چکیده
منابع مشابه
Polymorphisms in the TOLLIP Gene Influence Susceptibility to Cutaneous Leishmaniasis Caused by Leishmania guyanensis in the Amazonas State of Brazil
INTRODUCTION The clinical outcome to Leishmania-infection is determined by the individual adaptive immune T helper cell responses and their interactions with parasitized host cells. An early development of a proinflammatory immune response (Th1 response) is necessary for Leishmania-infection resolution. The Toll-interacting protein (TOLLIP) regulates human Toll-like receptors signaling pathways...
متن کاملthe study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولThe Role of Inflammatory, Anti-Inflammatory, and Regulatory Cytokines in Patients Infected with Cutaneous Leishmaniasis in Amazonas State, Brazil
The authors discuss in this paper the role of inflammatory, anti-inflammatory, and regulatory cytokines in patients infected with different species of Leishmania in Amazonas State, Brazil. A comparative analysis was made of serum concentrations of these cytokines in the peripheral blood of 33 patients infected with cutaneous leishmaniasis. The isolates were identified as Leishmania guyanensis, ...
متن کامل[American cutaneous leishmaniasis in the State of Acre, Brazil].
OBJECTIVE Present a statistical survey of American Cutaneous Leishmaniasis (ACL) in the State of Acre. METHODS Data were obtained from the forms of the "Campaign against Leishmaniasis", from January 1992 to December 1997. Descriptive statistical analysis was applied. RESULTS There were 2.557 registered cases. The highest prevalence was found at the microregion of Brasiléia (231.8 cases/10,0...
متن کاملAmerican cutaneous leishmaniasis in Brazil*
©2015 by Anais Brasileiros de Dermatologia Dear Editor, the case report on “American cutaneous leishmaniasis in Brazil” deals with an interesting topic.1 Bernardes Filho et al. reported on two new autochthonous cases of American cutaneous leishmaniasis in Brazil and state “the need for actions aiming at the early diagnosis and treatment of American cutaneous leishmaniasis cases.1” This report m...
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ژورنال
عنوان ژورنال: Genes & Immunity
سال: 2015
ISSN: 1466-4879,1476-5470
DOI: 10.1038/gene.2015.6